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H-D-PHG-OME HCL

  • Name H-D-PHG-OME HCL
  • CAS 19883-41-1
  • Purity 99%
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1.What is the H-D-PHG-OME HCL ?

(R)-(-)-2-Phenylglycine Methyl Ester Hydrochloride is an intermediate in the synthesis of Cephradine, a cephalosporin antibiotic. It functions as an acyl donor in the enzymatic synthetic process for cephradine synthesis.

DL-2-phenylglycine methyl ester hydrochloride
15028-40-7,13226-98-7

DL-2-phenylglycine methyl ester hydrochloride

L-2-phenylglycine methyl ester hydrochloride
15028-39-4,13226-98-7

L-2-phenylglycine methyl ester hydrochloride

D-phenylglycine methyl ester hydrochloride
19883-41-1,13226-98-7

D-phenylglycine methyl ester hydrochloride

Conditions
Conditions Yield
With sodium hexaflorophosphate; 1,3,5-Tris{[(S,S)-4,5-diphenyl-2-oxazolinyl]methyl}-2,4,6-triethylbenzene; In water-d2; chloroform-d1; at 25 ℃; optical yield given as %ee; Resolution of racemate;
With chiral stationary phase including (R)-naphthylethyl-carbamate-functionalized CF6; In ethanol; n-heptane; trifluoroacetic acid; at 20 ℃; Purification / work up;
methyl N-4'-methoxybenzylidenephenylglycinate
63430-99-9,88967-39-9,120328-94-1,67628-17-5

methyl N-4'-methoxybenzylidenephenylglycinate

L-2-phenylglycine methyl ester hydrochloride
15028-39-4,13226-98-7

L-2-phenylglycine methyl ester hydrochloride

D-phenylglycine methyl ester hydrochloride
19883-41-1,13226-98-7

D-phenylglycine methyl ester hydrochloride

Conditions
Conditions Yield
With (-)-O,O′-di-pivaloyl-L-tartaric acid; lithium diisopropyl amide; In tetrahydrofuran; diethyl ether; at -105 ℃; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

2.What is the CAS number for H-D-PHG-OME HCL ?

The CAS number of H-D-PHG-OME HCL is 19883-41-1.

More information of H-D-PHG-OME HCL 19883-41-1 are:

CAS?Number

19883-41-1

Density

1.126 g/cm3

Melting Point

189-191 °C(lit.)

Boiling Point

238.9 ºC at 760 mmHg

Flash Point

104.7 °C

Vapor Pressure

0.0412mmHg at 25°C

HS CODE

29224999

PSA

52.32000

LogP

2.36170

3.What are another words for H-D-PHG-OME HCL ?

Synonyms?for?H-D-PHG-OME HCL 19883-41-1:Benzeneaceticacid, a-amino-, methyl ester,hydrochloride, (R)-;Benzeneacetic acid, a-amino-, methyl ester, hydrochloride, (aR)- (9CI);Glycine, 2-phenyl-,methyl ester, hydrochloride, D- (8CI);((R)-2-Methoxy-2-oxo-1-phenylethyl)ammonium chloride;(R)-(-)-2-Phenylglycinemethyl ester hydrochloride;(R)-(-)-2-Phenylglycine methyl ester hydrochloride;(R)-2-Phenylglycine methyl ester hydrochloride;(R)-Methyl2-amino-2-phenylacetate hydrochloride;(R)-Phenylglycine methyl esterhydrochloride;D-Phenylglycine methyl ester hydrochloride;D-a-Aminophenylacetic acid methylester hydrochloride;Methyl (R)-amino(phenyl)acetate hydrochloride;Methyl(R)-phenylglycinate hydrochloride;Methyl D-phenylglycinate hydrochloride;Methyl D-a-phenylglycinate hydrochloride;Methyl D-a-phenylglycine hydrochloride;H-D-Phg-OMe·HCl;

4.What is the molecular formula of H-D-PHG-OME HCL?

The chemical formula of ?H-D-PHG-OME HCL is?C9H11NO2. ClH which containing 9 Carbon atoms,12 Hydrogen atoms,1 Nitrogen atoms,1 Oxygen atoms and 1 Chlorine atoms,and the molecular weight of??H-D-PHG-OME HCL?is 201.653.

5.What is H-D-PHG-OME HCL (19883-41-1) used for?

H-D-PHG-OME HCL, also known as (R)-(-)-2-Phenylglycine Methyl Ester Hydrochloride, is an intermediate in the synthesis of Cephradine, a cephalosporin antibiotic. It is a white solid with chemical properties that make it a crucial component in the production of this antibiotic.

InChI:InChI=1/C9H11NO2.ClH/c1-12-9(11)8(10)7-5-3-2-4-6-7;/h2-6,8H,10H2,1H3;1H/t8-;/m1./s1

Relevant articles related to H-D-PHG-OME HCL:

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Uemura, Takahito,Saito, Yusuke,Sonoda, Motohiro,Tanimori, Shinji

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Synthesis of novel 1-[(1-ethoxymethylene)amino]imidazol-5(4H)-ones and 1,2,4-triazin-6(5H)-ones from optically active α-aminocarboxylic acid hydrazides

Kudelko, Agnieszka,Zieliński, Wojciech,Jasiak, Karolina

supporting information, p. 4637 - 4640 (2013/08/23)

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