1-(4-CHLOROPHENYL)-1-CYCLOPENTANECARBONYLCHLORIDE
- Name 1-(4-CHLOROPHENYL)-1-CYCLOPENTANECARBONYLCHLORIDE
- CAS 71501-44-5
- Purity 99%
Product Details
Buy Quality 1-(4-CHLOROPHENYL)-1-CYCLOPENTANECARBONYLCHLORIDE 71501-44-5 In Stock with Immediately Delivery
- Molecular Formula: C12H12 Cl2 O
- Molecular Weight: 243.133
- Vapor Pressure: 0.000428mmHg at 25°C
- Refractive Index: 1.5545-1.5565
- Boiling Point: 315.8°C at 760 mmHg
- Flash Point: 126.3°C
- PSA: 17.07000
- Density: 1.283g/cm3
- LogP: 3.91720
1-(4-CHLOROPHENYL)-1-CYCLOPENTANECARBONYLCHLORIDE(Cas 71501-44-5) Usage
InChI:InChI=1/C12H12Cl2O/c13-10-5-3-9(4-6-10)12(11(14)15)7-1-2-8-12/h3-6H,1-2,7-8H2
71501-44-5 Relevant articles
Achiral Derivatives of Hydroxamate AR-42 Potently Inhibit Class i HDAC Enzymes and Cancer Cell Proliferation
Tng, Jiahui,Lim, Junxian,Wu, Kai-Chen,Lucke, Andrew J.,Xu, Weijun,Reid, Robert C.,Fairlie, David P.
supporting information, p. 5956 - 5971 (2020/06/05)
AR-42 is an orally active inhibitor of h...
Synthesis and Biological Activity of Arylcyclopentane-1-carboxylic Acids Aminoesters
Aghekyan,Mkryan,Tsatinyan,Gasparyan
, p. 1051 - 1054 (2019/07/03)
1-Arylcyclopentane-1-carboxylic acids we...
Synthesis of 4H-1,3-Benzoxazines via Metal- and Oxidizing Reagent-Free Aromatic C-H Oxygenation
Xu, Fan,Qian, Xiang-Yang,Li, Yan-Jie,Xu, Hai-Chao
supporting information, p. 6332 - 6335 (2017/12/08)
An unprecedented electrochemical aromati...
Synthesis of β-, γ-, and δ-lactams via Pd(II)-catalyzed C-H activation reactions
Wasa, Masayuki,Yu, Jin-Quan
supporting information; experimental part, p. 14058 - 14059 (2009/03/11)
Pd(II)-catalyzed intramolecular aminatio...
71501-44-5 Process route
-
-
80789-69-1
1-(4-chlorophenyl)cyclopentane-1-carboxylic acid
-
-
71501-44-5
1-(4-chlorophenyl)cyclopentane-1-carboxylic acid chloride
| Conditions | Yield |
|---|---|
|
With
thionyl chloride;
In
benzene;
for 8h;
Heating;
|
60.1%
|
|
With
thionyl chloride; N,N-dimethyl-formamide;
In
hexane;
for 2h;
Heating;
|
|
|
With
thionyl chloride;
In
toluene;
for 4h;
Heating;
|
|
|
In
thionyl chloride; diethyl ether;
|
|
|
With
oxalyl dichloride;
|
|
|
With
oxalyl dichloride; N,N-dimethyl-formamide;
In
dichloromethane;
at 20 ℃;
for 3h;
Inert atmosphere;
|
|
|
With
thionyl chloride;
In
benzene;
for 6h;
Reflux;
|
|
|
With
chlorinating agent;
In
dichloromethane;
at 0 ℃;
|
|
|
With
thionyl chloride;
In
benzene;
for 6h;
Heating;
|
-
-
64399-26-4
1-(4-chlorophenyl)cyclopentanecarboxylic acid
-
-
71501-44-5
1-(4-chlorophenyl)cyclopentane-1-carboxylic acid chloride
| Conditions | Yield |
|---|---|
|
Multi-step reaction
with
2
steps
1: 75.5 percent / KOH / various solvent(s) / 12 h / Heating
2: 60.1 percent / SOCl2
/ benzene / 8 h / Heating
With
potassium hydroxide; thionyl chloride;
In
benzene;
|
|
|
Multi-step reaction
with
2
steps
1: potassium hydroxide / ethylene glycol / 9 h / Reflux
2: thionyl chloride / benzene / 6 h / Reflux
With
thionyl chloride; potassium hydroxide;
In
ethylene glycol; benzene;
|
|
|
Multi-step reaction
with
2
steps
1: potassium hydroxide / ethylene glycol / 9 h / Heating
2: thionyl chloride / benzene / 6 h / Heating
With
thionyl chloride; potassium hydroxide;
In
ethylene glycol; benzene;
|
71501-44-5 Upstream products
-
80789-69-1
1-(4-chlorophenyl)cyclopentane-1-carboxylic acid
-
64399-26-4
1-(4-chlorophenyl)cyclopentanecarboxylic acid
-
140-53-4
p-chlorobenzyl cyanide
-
52449-43-1
(4-chloro-phenyl)-acetic acid methyl ester
71501-44-5 Downstream products
-
143407-73-2
Sodium; (6R,7R)-7-{[1-(4-chloro-phenyl)-cyclopentanecarbonyl]-amino}-3-methyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate
-
143407-77-6
Sodium; (6R,7R)-3-acetoxymethyl-7-{[1-(4-chloro-phenyl)-cyclopentanecarbonyl]-amino}-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate
-
1387992-42-8
C14 H18 ClNO2
-
911056-42-3
1-(4-chloro-phenyl)-cyclopentanecarboxylic acid (thiophen-2-ylmethyl)-amide