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2-[[4-[3-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]phenyl]sulphonyl]ethyl hydrogen maleate

  • Name 2-[[4-[3-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]phenyl]sulphonyl]ethyl hydrogen maleate
  • CAS 3663-96-5
  • Purity 99%
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Product Details

Reliable Quality 2-[[4-[3-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]phenyl]sulphonyl]ethyl hydrogen maleate 3663-96-5 Hot Sale with Chinese Manufacturer

  • Molecular Formula: C21H19 Cl N2 O6 S
  • Molecular Weight: 462.911
  • Vapor Pressure: 3.3E-21mmHg at 25°C 
  • Boiling Point: 710.9°Cat760mmHg 
  • Flash Point: 383.7°C 
  • PSA: 121.72000 
  • Density: 1.4g/cm3 
  • LogP: 3.49350 

2-[[4-[3-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]phenyl]sulphonyl]ethyl hydrogen maleate(Cas 3663-96-5) Usage

Drug class

Nonsteroidal anti-inflammatory drug (NSAID)

Mechanism of action

Inhibits the production of prostaglandins

Indications

Used to reduce pain and inflammation in conditions such as arthritis and musculoskeletal disorders

Prodrug

Inactive until metabolized in the body to its active form, sulindac sulfide

Route of administration

Tablets

Side effects

Gastrointestinal irritation, renal impairment, cardiovascular complications

Caution

Use under the supervision of a healthcare professional, follow prescribed dosage and duration of treatment

General Description

2-[[4-[3-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]phenyl]sulphonyl]ethyl hydrogen maleate, also known as Sulindac, is a nonsteroidal anti-inflammatory drug (NSAID) that is used to reduce pain and inflammation in conditions such as arthritis and other musculoskeletal disorders. It works by inhibiting the production of prostaglandins, which are chemicals in the body that cause pain and inflammation. Sulindac is a prodrug, which means it is inactive until it is metabolized in the body to its active form, sulindac sulfide. It is commonly available in the form of tablets, and its use is associated with potential side effects such as gastrointestinal irritation, renal impairment, and cardiovascular complications. Therefore, it is important to use this medication under the supervision of a healthcare professional and to follow the prescribed dosage and duration of treatment.

InChI:InChI=1/C21H19ClN2O6S/c22-16-3-1-15(2-4-16)19-11-12-24(23-19)17-5-7-18(8-6-17)31(28,29)14-13-30-21(27)10-9-20(25)26/h1-10H,11-14H2,(H,25,26)/b10-9-

3663-96-5 Process route

2-({4-[3-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]phenyl}sulfonyl)ethyl hydrogen maleate
3663-96-5

2-({4-[3-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]phenyl}sulfonyl)ethyl hydrogen maleate

Conditions
Conditions Yield
entspr. Alkohol, entspr .Saeureanhydrid;

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